Effect of Nasil drop (sesame based black seeds) versus placebo on treatment of chronic rhinosinusitis

Effect of Nasil drop (sesame based black seeds) versus placebo on treatment of chronic rhinosinusitis: a triple blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201703079014N149

Enrollment

Registered

2017-03-12

Start date

2017-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic rhinosinusitis. Chronic sinusitis, unspecified

Interventions

Intervention 1: Intervention group: Nasil drop (sesame based black seeds) one drop in the right nostril at the first night, one drop in the left nostril at the second night, two drops in the right nos

three drops in the right nostril at the fifth night and three drops in the left nostril at the sixth night

then, the drop will be quit for one week and again drop will be started the same way once more. Intervention 2: Control group: Placebo drop (including distilled water) one drop in the right nostril at

then, the drop will be quit for one week and again drop will be started the same way once more.

Treatment - Drugs

Placebo

Intervention group: Nasil drop (sesame based black seeds) one drop in the right nostril at the first night, one drop in the left nostril at the second night, two drops in the right nostril at the thir

Control group: Placebo drop (including distilled water) one drop in the right nostril at the first night, one drop in the left nostril at the second night, two drops in the right nostril at the third

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 18 to 64 years; chronic rhinosinusitis. Exclusion criteria: Pregnancy; fever; immunosuppression; nasal polyp; sensitivity to black seeds or sesame.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Status of rhinosinusitis. Timepoint: before intervention, immediately after intervention and 3 weeks later. Method of measurement: based on Vas score.;Status of rhinosinusitis. Timepoint: before intervention, immediately after intervention and 3 weeks later. Method of measurement: based on Snot-22 score.;Status of rhinosinusitis. Timepoint: before intervention, immediately after intervention and 3 weeks later. Method of measurement: based on endoscopic.	—

Measure

Time frame

Status of rhinosinusitis. Timepoint: before intervention, immediately after intervention and 3 weeks later. Method of measurement: based on Vas score.;Status of rhinosinusitis. Timepoint: before intervention, immediately after intervention and 3 weeks later. Method of measurement: based on Snot-22 score.;Status of rhinosinusitis. Timepoint: before intervention, immediately after intervention and 3 weeks later. Method of measurement: based on endoscopic.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Tahereh Mozayyan

Besat Hospital

dr_t_mozayyan@yahoo.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026