Comparison of the effect of articaine and mepivacaine in inferior alveolar nerve block for removal of impacted mandibular third molar

Comparison of the effect of 4%articaine and 3%mepivacaine in inferior alveolar nerve block for removal of impacted mandibular third molar

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170307032929N2

Enrollment

Registered

2020-09-08

Start date

2019-07-01

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

removal of impacted mandibular third molar. Impacted teeth

Interventions

Intervention 1: Intervention group 1: Receives a part of the mandible that has a maximum of 3 carpoles of 4% articaine anesthesia with epinephrine 1: 100000 and is produced by the elixir factory by lo

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: People between the ages of 18-35. Complete patient consent to participate in the study. Those in whom mandibular third molar surgery is bilaterally indicated. Indication of block injection on both sides of the mandible.

Exclusion criteria

Exclusion criteria: Systemic and neurological diseases. Allergy to sulfite (allergic asthma) or local anesthetic. Smoking, alcohol, drugs. Any acute infection and swelling.

Design outcomes

Primary

Measure	Time frame
ONSET TIME OF ANESTHESIA. Timepoint: Immediately after the injection until the time of tingling or numbness in the lower lip is recorded with a stopwatch. Method of measurement: Immediately after the injection until the time of tingling or numbness in the lower lip is recorded with a stopwatch.;The amount of pain during extraction of the wisdom tooth of the mandible. Timepoint: The patient was asked the amount of pain by the Visual Analogue Scale system during the extraction of the impacted wisdom tooth with the alveolar. Method of measurement: The amount of pain was asked by the patient by the Visual Analogue Scale system during the extraction of the impacted wisdom tooth with the alveolar and was recorded in the relevant form.	—

Measure

Time frame

ONSET TIME OF ANESTHESIA. Timepoint: Immediately after the injection until the time of tingling or numbness in the lower lip is recorded with a stopwatch. Method of measurement: Immediately after the injection until the time of tingling or numbness in the lower lip is recorded with a stopwatch.;The amount of pain during extraction of the wisdom tooth of the mandible. Timepoint: The patient was asked the amount of pain by the Visual Analogue Scale system during the extraction of the impacted wisdom tooth with the alveolar. Method of measurement: The amount of pain was asked by the patient by the Visual Analogue Scale system during the extraction of the impacted wisdom tooth with the alveolar and was recorded in the relevant form.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFina Navi

Islamic Azad University

f_navi@dentaliau.ac.ir+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026