Diabetes. Type 2 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group1: Capsule content of 0.5gr Cinnamomum and 10^8 colony per unit Lactobacillus Acidufilus, orally for 90 days. Intervention 2: Intervention group2: Capsule content of
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 25 to 65 years Fasting blood sugar between 126 to 250 mg/dl HbA1c less than 7.5
Exclusion criteria
Exclusion criteria: People who are younger than 25 years old and older than 65 years old People with severe diabetes (The blood sugar more than 250) Women in pregnancy and lactation periods People who consume special drugs (drugs which affect on blood sugar, such as corticosteroids, diuretics) Usage insulin, vitamin supplements and herbal Change in diabetes medicine during last 6 months People who don't tolerate lactose Patients who have artificial heart valve Patients with short bowel syndrome Patients with chronic liver , renal, lung, diseases and uncontrollable blood pressure Patients with allergy patients with special diet or physical activity Diabetic type2 patients who need to use insulin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood sugar (FBS). Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: Glucometer.;HbA1c. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;Superoxide dismutase enzyme. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;Glutathione proxidase. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;Catalase. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;OxLDL. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;AOPP. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: laboratory.;AGEs. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: laboratory.;FRAP. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: laboratory.;TG. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: Laboratory.;Cholesterol. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: Laboratory.;LDL. Timepoint: Before intrvention and at the end of 3 month of begining. Method of measurement: Laboratory.;HDL. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: Laboratory.;IL10. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;TNFa. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: kit.;CRP. Timepoint: Before intrvention and at the end of 3 month of begining the research. Method of measurement: Laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects and liver toxicity. Timepoint: Within the reserch and until 1 month later. Method of measurement: Asking patients and observation if is needed. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahareh Tavakolifar
Karaj University of Medical Sciences
Outcome results
None listed