Comparison of two methods of inhalation and intravenous anesthesia on the incidence of complications in children with epidermolysis bullosa

Comparison of the effect of inhalation and intravenous anesthesia on the incidence of intraoperative and postoperative complications in children with epidermolysis bullosa undergoing hand reconstructive surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170301032837N5

Enrollment

128

Registered

2025-09-20

Start date

2025-07-23

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidermolysis Bulosa. Epidermolysis bullosa, unspecified

Interventions

Intervention 1: Intervention group: Intervention group A: In this group, after induction of anesthesia, only intravenous drugs are used to maintain anesthesia. Induction of anesthesia is performed wit

Eligibility

Sex/Gender

All

Age

3 Years to 14 Years

Inclusion criteria

Inclusion criteria: A patient with epidermolysis bullosa Age between 3 and 14 years Consent to participate in the research by parents

Exclusion criteria

Exclusion criteria: Heart diseases Respiratory diseases kidney Diseases Congenital and other genetic disorders History of drug sensitivity History of seizures

Design outcomes

Primary

Measure	Time frame
Bradycardia. Timepoint: During anesthesia and recovery period. Method of measurement: Heart rate monitoring.;Tachycardia. Timepoint: During anesthesia and recovery period. Method of measurement: Heart rate monitoring.;Arterial oxygen saturation percentage (SPO2). Timepoint: During anesthesia and recovery. Method of measurement: Pulse Oximeter.;Respiratory apnea. Timepoint: During anesthesia and recovery period. Method of measurement: Capnography and observation.;Laryngospasm. Timepoint: During anesthesia and recovery period. Method of measurement: Observation and Capnography.;Skin injuries. Timepoint: During anesthesia and recovery period. Method of measurement: Observation.;Nausea and Vomiting. Timepoint: During anesthesia and recovery period. Method of measurement: Observation.;EmergenceAgitation. Timepoint: Recovery. Method of measurement: Observation.	—

Measure

Time frame

Bradycardia. Timepoint: During anesthesia and recovery period. Method of measurement: Heart rate monitoring.;Tachycardia. Timepoint: During anesthesia and recovery period. Method of measurement: Heart rate monitoring.;Arterial oxygen saturation percentage (SPO2). Timepoint: During anesthesia and recovery. Method of measurement: Pulse Oximeter.;Respiratory apnea. Timepoint: During anesthesia and recovery period. Method of measurement: Capnography and observation.;Laryngospasm. Timepoint: During anesthesia and recovery period. Method of measurement: Observation and Capnography.;Skin injuries. Timepoint: During anesthesia and recovery period. Method of measurement: Observation.;Nausea and Vomiting. Timepoint: During anesthesia and recovery period. Method of measurement: Observation.;EmergenceAgitation. Timepoint: Recovery. Method of measurement: Observation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehrooz Zaman

Iran University of Medical Sciences

zaman.b@iums.ac.ir+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026