The effect of nasal phenylephrine drops on palatoplasty blood loss

Evaluation of the effect of phenylephrine drops on the blood loss during and after reconstructive surgery of cleft palate in children

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170301032837N4

Enrollment

Registered

2021-05-12

Start date

2021-05-22

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cleft palate. Cleft palate

Interventions

Intervention 1: Intervention group:After induction of anesthesia and before the preparation of the operation, two drops of phenylephrine 0.25% are instilled in each nostril. Intervention 2: Control gr

Eligibility

Sex/Gender

All

Age

6 Months to 2 Years

Inclusion criteria

Inclusion criteria: Candidate for cleft palate surgery Age between 6 months to two years Weight between 7 to 21 kg

Exclusion criteria

Exclusion criteria: Anemia Cardiovascular disorders Coagulopathies Coagulopathies in Family Any congenital and genetic disorders

Design outcomes

Primary

Measure	Time frame
Intraoperative blood loss. Timepoint: During the operation and the end of the operation. Method of measurement: Counting and weighing blood gases, blood in suctioning bottle.	—

Secondary

Measure	Time frame
Surgeon satisfaction with the operation field. Timepoint: At the end of surgery. Method of measurement: Likert scale, Boozart scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehrooz Zaman

Iran University of Medical Sciences

zaman.b@iums.ac.ir+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026