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The effects of Aminophyllin on recovery duration, postoperative shivering and PONV with elective general surgery

The effects of Aminophyllin on recovery duration, postoperative shivering and PONV with elective general surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017022631642N1
Enrollment
88
Registered
2017-02-26
Start date
2017-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative shivering. Other complications of anaesthesia

Interventions

Intervention 1: 4 mg kg aminophylline in 10 mL of saline is diluted and infusion before surgery. Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in reco
Treatment - Drugs
Placebo
4 mg kg aminophylline in 10 mL of saline is diluted and infusion before surgery. Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in recovery, nausea in
Ten mL of saline is given before surgery Vital signs, duration of recovery, the degree of shivering and need to treatment shiveringin in recovery, nausea in recovery and 6,24 houre after surgery will

Sponsors

Ardebil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with a history of cardiovascular, pulmonary, or thyroid disease; dysautonomia; fever; aminophylline intake within a day before surgery; and who received transplant, will leave from this study. All patientsl will enter referred for elective general surgery to Imam Khomeini hospital in Ardebil.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Shivering. Timepoint: At the time of recovery. Method of measurement: Scale: 0 = no shivering; 1 = no visible muscle activity but piloerection, peripheral vasoconstriction, or both are present (other causes excluded); 2 = muscular activity in only one muscle group; 3 = moderate muscular activity in more than one muscle group but no generalized shaking; 4 = violent muscular activity that involves the whole body.

Secondary

MeasureTime frame
Nausea. Timepoint: At the time of recovery, 6 and 24 hours after surgery. Method of measurement: Scale: no nausea = 0; mild nausea = 1; moderate nausea = 2; severe nausea= 3.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohadeseh Esmailnejad

Ardebil University of Medical Sciences

m.esmaeil@arums.ac.ir+98 44 3427 2643

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026