Efficacy of Donepezil in Amnisia due to Electro Convulsive Therapy

Efficacy of Donepezil in cognitive impairments of patients under Electro Convulsive Therapy (Randomized Double blind Clinical Trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017022532766N1

Enrollment

Registered

2017-04-03

Start date

2017-04-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia,Schizoaffective,Mood dosorders and Obsessive-compulsive disorders. Schizophrenia ,Schizoaffective disorder.Bipolar affective disoeder.Obssessive_compulsive disorder,Mood disorder(manic episode).Mood disorder(Depressive episode)

Interventions

Intervention 1: Donepezil 5 mg capsules every night in the intervention group. Intervention 2: control group received placebo capsules per night.

Prevention

Placebo

Donepezil 5 mg capsules every night in the intervention group

control group received placebo capsules per night

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :Patients referring to Sanandaj Qods Hospital ; Age between 18-60 years old; 2-8 sessions Electro Convulsive Therapy; The Patient who fill out the testimonial form; and Exclusion criteria: Alcohol and substance dependence except Caffeine and Nicotine in past 3 months; History of Epilepsy; Proven Intelligent Disability or diagnosed with assistant; History of Delirium, Dementia and Cognitive Disorders ;Pregnancy and breast-feeding; History of using Doneprzil in past 3 months; History of using Paroxetine and Ketoconazol; Donepezil sensitivity; History of Cardiovascular disease; History of Brain Stroke in past 6 months; Head trauma and surgery or traumatic Brain injury in past year

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Memory. Timepoint: 1day before begining and after the Electro Convulsive Therapy. Method of measurement: wechsler.;Memory. Timepoint: 1day before begining and after ending the Electro Convulsive Therapy. Method of measurement: mini mental status examination.	—

Secondary

Measure	Time frame
Tremor. Timepoint: During interventiin. Method of measurement: Patient Self Report.;Cofusion. Timepoint: During interventiin. Method of measurement: Patient Self Report.;Headache. Timepoint: During interventiin. Method of measurement: Patient Self Report.;Nausea. Timepoint: During interventiin. Method of measurement: Patient Self Report.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHojat Sfandyari

Qods Hospital

esfandyari89@gmail.com+98 87 3366 4653

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026