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The effect of bupivacaine and fentanyl level of sensory and motor in elderly patients

The effect of low dose bupivacaine and fentanyl in spinal anesthesia on the level of sensory and motor block in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201702226148N4
Enrollment
80
Registered
2017-06-02
Start date
2015-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sensory-Motor Block. Symptoms and signs involving the nervous and musculoskeletal systems

Interventions

Intervention 1: In intervention group, standard regimen including bupivacaine 0.5 % (7.5 gr Astra Zeneca, Sweden) and Fentanyl (25 µgr, Rotexmedic, Germany) was prescribed. Intervention 2: In control
Treatment - Drugs
In intervention group, standard regimen including bupivacaine 0.5 % (7.5 gr Astra Zeneca, Sweden) and Fentanyl (25 µgr, Rotexmedic, Germany) was prescribed.
In control group, standard regimen including bupivacaine 0.5 % (7.5 gr Astra Zeneca, Sweden)

Sponsors

Vice Chancellor for Research, Babol Univercity of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 65 to 85 candidates for prostatectomy Exclusion criteria: patients with a history of bleeding disorders, neurological diseases, loss of consciousness, presence of infection at the injection site

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Level of sensory block. Timepoint: Minutes:10 ,20 after spinal anesthesia. Method of measurement: Sensory level was assessed using the tip of a needle sterilized and with alcohol cotton.

Secondary

MeasureTime frame
Motor block. Timepoint: Minutes: 10,20,30 and in the end of surgery and 2hours after spinal anesthesia. Method of measurement: Motor block was assessed and recorded using Bromage Scale( BS=0 full knee and foot flexion, BS=1 ability to move knee, BS=2 ability to move feet only, BS=3 full motor block).;Patient s blood pressure. Timepoint: Blood pressure was monitored and recorded every 3 minutes for the first 10 minutes following spinal anesthesia and then every 5 minutes until completion of surgery. Method of measurement: Noninvasive blood pressure cuff.;Patient s heart rate. Timepoint: Heart rate was monitored and recorded every 3 minutes for the first 10 minutes following spinal anesthesia and then every 5 minutes until completion of surgery. Method of measurement: Monitoring of ECG and Pulse oximetry.;Pain. Timepoint: Minutes: 10,20,30 during surgery. Method of measurement: VAS (Visual Analogues Scale).;Nausea and vomiting. Timepoint: During surgery. Method of measurement: Question & observation.;Respiratory depression. Timepoint: After spinal anesthesia. Method of measurement: Examination& observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maedeh Jafarzadeh

Babol University of Medical Scince

dr.jafarzadeh2011@gmail.com+98 11 3223 8284

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026