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The effect of Curcumin on serum lipid profiles and systemic inflammation in hemodialysis patients

The effect of Curcumin on serum lipid profiles and systemic inflammation in hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017022232719N1
Enrollment
64
Registered
2017-05-15
Start date
2017-04-25
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialyzied kidney desease patients. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention 1: Intervention group: 80 mg Sina Curcumin medicine ? once in day in during 2months . Intervention 2: Control group: placebo contains 0/5 mg starch ? is given once in day during two mo
Prevention
Control group: placebo contains 0/5 mg starch ? is given once in day during two months.
Intervention group: 80 mg Sina Curcumin medicine ? once in day in during 2months .

Sponsors

Vice chancellor for research,Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: IInclusion criteria: The patient's tendency to participating in study and signing approval form? Having a history of at least 6 months of dialysis? age between 25-75 years old ? BMI between 18.5 to 30? Lack of infectious disease, particularly hepatitis? Avoiding the use of no steroidal anti-inflammatory drugs, Nicotinic Acid, estrogen, progesterone and Curcumin supplementation for at least one month before the start of the study? Lack of drug addiction? Lack of severe heart disease, liver failure and thyroid, severe gastrointestinal bleeding and peptic ulcer disease, cholelithiasis, pregnancy or lactation Exclusion criteria: Increasing of potassium in patients' blood during the study? unwilling to continue to participate?Death of the patient? Performing kidney transplantation? Increasing in dose of anti-fat drugs? Changing patient's lifestyle or diet during the study? The use of herbal medicines for lipid lowering during the study? No adherence to study intervention of at least 9 tablets during two months of interference

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Trigliceride? Cholestrol? LDL? HDL ? hs crp. Timepoint: Before entrances and after entrances. Method of measurement: Blood test.

Secondary

MeasureTime frame
BUN? Cr? Serum Albumin ? Adequacy of Dialysis ? BMI. Timepoint: Before entrances and after entrance. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDoctor Koushki

Sabzevar University of Medical Sciences

kooshki.nutr@gmail.com+98 51 4401 1370

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026