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The effect of low calorie diets on anthropometric, glycemic, cardiovascular and hormonal factors in people with polycystic ovary syndrome

Evaluation of the effect of Modified Alternate Day Fasting in comparison with energy restriction (Calorie Restriction) on anthropometric indices, glycemic markers, lipid parameters and hormone levels in people with polycystic ovary syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170221032698N2
Enrollment
44
Registered
2021-09-20
Start date
2021-09-23
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: The normal diet of individuals is observed and followed for 2 weeks. Then, the ADF group consumed 25% of their energy on 3 days of the week (Saturday, Monday, Wedne

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women with polycystic ovary syndrome Age 25- 45 years 25 = BMI = 40 kg/m2 Body weight more than 5 kg has not changed during the last 3 months No fasting for 3 months prior to the beginning of the study Absence of diseases such as diabetes, cardiovascular, kidney, thyroid disorders, liver diseases, etc. Do not take medication, including drug that lower blood sugar, blood pressure and lipids. Also drugs that affect glycemic index and lipid parameters. No smoking and alcohol Intense physical inactivity Failure to follow specific diets People who, after explaining the work, are willing to cooperate and answer questions and perform experiments.

Exclusion criteria

Exclusion criteria: Lack of cooperation of participants in different stages of project implementation People who lose the conditions to enter the study

Design outcomes

Primary

MeasureTime frame
Body Weighy. Timepoint: Two times, before and after dietary intervention. Method of measurement: Weight with minimal coverage and without shoes using a SECA weight scale with an accuracy of 100 grams.;BMI. Timepoint: Two times, before and after dietary intervention. Method of measurement: Divide weight (kg) by height squared (m2).;Waist circumference. Timepoint: Two times, before and after dietary intervention. Method of measurement: Between the lower margin of the last rib and the crown of the iliac bone at the level of the umbilicus and at the end of natural exhalation from the garment.;Blood pressure. Timepoint: Two times, before and after dietary intervention. Method of measurement: Blood pressure is measured using a mercury sphygmomanometer after sitting for 10 minutes.;Fasting blood sugar. Timepoint: Two times, before and after dietary intervention. Method of measurement: In the FBS test, the patient should fast for 10-12 hours. Its normal amount varies according to the kit and test method. In the enzymatic method, FBS in normal adults is 110-70 mg / dl.;Total cholesterol. Timepoint: Two times, before and after dietary intervention. Method of measurement: The amount (TC) is measured by enzymatic methods.;HDL. Timepoint: Two times, before and after dietary intervention. Method of measurement: The amount (HDL) is measured by enzymatic methods.;Triglyceride. Timepoint: Two times, before and after dietary intervention. Method of measurement: The amount (TG) is measured by enzymatic methods.;LDL. Timepoint: Two times, before and after dietary intervention. Method of measurement: Serum LDL will also be calculated using the Friedwald equation.;Fat Mass. Timepoint: Two times, before and after dietary intervention. Method of measurement: Body composition analyzer.;Fat Free Mass. Timepoint: Two times, before and after dietary intervention. Method of measurement: Body composition analyzer.;Fasting insulin. Timepoint: Two times, before and after dietary intervention. Meth

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh azizi

Yazd University of Medical Sciences

forough.nutritionist@gmail.com+98 35 3728 0226

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026