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Comparing the effect of persica and chlorhexidine on the prevention of ventilator Associated pneumonia in patient admitted in ICU

Effect of persica and chlorhexidine on the prevention of ventilator Associated pneumonia

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017022032676N1
Enrollment
50
Registered
2017-04-22
Start date
2015-09-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ventilator associated pneumonia. Pneumonia due to Streptococcus pneumoniae

Interventions

Intervention 1: chlorhexidin mouth wash. Intervention 2: Persica mouth wash.
Treatment - Drugs
chlorhexidin mouth wash
Persica mouth wash

Sponsors

Vice Chanceller for Research, Mazandran University of Medical Sciense
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Age between 18 and 65; be intubated; be under mechanical ventilation in 48 hours after admission. Exclusion criteria: dissatisfaction with the patient at any time in the study; Re - intubation; autoimmune diseases and malignancies; history of radiotherapy and the use of immunosuppressive drugs such as corticosteroids and immunosuppressive diseases; mouthwash allergy history; asthma and allergic rhinitis and dermatitis; previous use of antibiotics in the hospital in two weeks before; history of any antimicrobial mouthwash two weeks before hospitalization; Oral mucositis and periodontal disease; patients with pneumonia; pregnant women; history of lung disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pneumonia. Timepoint: 3 days. Method of measurement: CPIS.

Secondary

MeasureTime frame
Complication. Timepoint: 3 days. Method of measurement: examination.;Intubation duration. Timepoint: extubation. Method of measurement: examination.;ICU mortality. Timepoint: dead time. Method of measurement: observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFrashad Hassanzadeh Kiabi

Department of Anesthesiology, Mazandaran University of Medical Science

fhasanzadehk@mazums.ac.ir+98 113337770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026