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Investigating the effect of dexamethasone with lidocaine compared to lidocaine on the time and intensity of axillary block analgesia in upper extremity orthopedic surgeries

Investigating the effect of dexamethasone with lidocaine compared to lidocaine on the time and intensity of axillary block analgesia in upper extremity orthopedic surgeries

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170220032676N4
Enrollment
72
Registered
2025-06-15
Start date
2025-07-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain in upper limb orthopedic surgeries. Dexamethasone, lidocaine, analgesia

Interventions

Intervention 1: Intervention group: Patients in the intervention group will receive an axillary brachial plexus block with a mixture of 34 mL of 1.5% lidocaine and 2 mL (8 mg) dexamethasone. The solut

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 75 years/ Candidate for orthopedic surgery of the hand or forearm / Normal level of consciousness/ No underlying diseases mentioned in the exclusion criteria

Exclusion criteria

Exclusion criteria: Failure to achieve block (complete anesthesia) Patients with multiple injuries in other parts of the body due to severe trauma Peptic ulcer disease Diabetes mellitus Liver or kidney failure Pregnant women Those receiving any premedication (including opioids, benzodiazepines, and clonidine) will be excluded from the study

Design outcomes

Primary

MeasureTime frame
Duration of analgesia after axillary block. Timepoint: Immediately after completion of the axillary block, the duration of analgesia will be measured as the time interval from the end of drug injection until the first request for analgesic medication by the patient after surgery. If needed, additional measurements will be recorded at 1, 2, 4, 6, and 12 hours postoperatively. Method of measurement: The duration of analgesia will be measured by direct patient questioning and recording the time from the end of drug injection until the first request for analgesic medication. The time will be recorded in minutes using a digital clock.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarshad Hassanzadeh

Mazandaran University of Medical Sciences

Fhasanzadehk@mazums.ac.ir+98 917 500 1036

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026