Neonatal jaundice. Neonatal jaundice, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Phenobarbital, oral, 3.5 mg/kg/day, for the first 7 days after discharge. Intervention 2: Control group: no intervention.
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 10 Days
Inclusion criteria
Inclusion criteria: Have a major risk factors for development of severe hyperbilirubinemia Hospitalized because of hyperbilirubinemia in the first 10 days of birth
Exclusion criteria
Exclusion criteria: Major congenital malformations Gestational age <35 weeks Weight <2500 g at birth History of blood transfusion History of IVIG administration History of maternal use of phenobarbital in the last month of pregnancy Whose parents refused to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of readmissions for neonatal jaundice. Timepoint: 7 days after discharge. Method of measurement: Physician examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean serum bilirubin levels. Timepoint: Before intervention and 1, 3, 5, 7 day after intervention. Method of measurement: Blood test.;Adverse effects of phenobarbital (feed intolerance, lethargy, apnea and cyanotic spells). Timepoint: During 1 weeks after intervention. Method of measurement: Physician examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Aghaali
Ghoum University of Medical Sciences
Outcome results
None listed