Comapring impact of Bles versus Curosurf in respiratory distress of preterm infants

clinical trial for comparing impact of Bles versus Curosurf in management of respiratory distress syndrome in preterm neonates hospitalized in neonatal intensive care unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017021418994N3

Enrollment

240

Registered

2017-04-07

Start date

2016-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Dystress Syndrome. Hyaline membrane disease

Interventions

Intervention 1: Advising Cursourf with 2.5 cc/kg slowly via neonatal trachea with vital sign control and cardiopulmonary monitoring. Intervention 2: Advising Bles 5 cc/kg rapidly via neonatal trachea

Treatment - Drugs

Advising Cursourf with 2.5 cc/kg slowly via neonatal trachea with vital sign control and cardiopulmonary monitoring

Advising Bles 5 cc/kg rapidly via neonatal trachea with vital sign control and cardiopulmonary monitoring

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: less than 34 weeks gestational age; Confirmed Respiratory Distress Syndrome Exclusion Criteria: Confirmed Sepsis; Congenital heart diseases; Pulmonary hemorrhage; Congenital Pneumonia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Oxygenic Index. Timepoint: Before and 12 hours after intervention. Method of measurement: According ABG and ventilator indices.;Ventilation period. Timepoint: Before and 12 hours after intervention. Method of measurement: Neonates medical records.;NCPAP period. Timepoint: before and 12 hours after Intervention. Method of measurement: Neonates medical records.;Hospitalization time. Timepoint: After Intervention. Method of measurement: Neonates medical records.	—

Measure

Time frame

Oxygenic Index. Timepoint: Before and 12 hours after intervention. Method of measurement: According ABG and ventilator indices.;Ventilation period. Timepoint: Before and 12 hours after intervention. Method of measurement: Neonates medical records.;NCPAP period. Timepoint: before and 12 hours after Intervention. Method of measurement: Neonates medical records.;Hospitalization time. Timepoint: After Intervention. Method of measurement: Neonates medical records.

—

Secondary

Measure	Time frame
Mortality rate. Timepoint: Before and 12 hours after intervention. Method of measurement: medical folder of neonates.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Zeinab Kheradmand

Kerman University of Medical Sciences

vcr@kmu.ac.ir+98 34 3132 5700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026