Comparison the effect of lidocaine local analgesia in combination with and without ketorolac in patients with forearm fracture

Comparison the effect of 0.5% lidocaine local analgesia in combination with and without ketorolac in Bier's Block method in patients with forearm fracture

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017021232520N1

Enrollment

Registered

2017-04-10

Start date

2016-06-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Forearm fracture. Fracture of forearm

Interventions

Intervention 1: First group of intervention: intravenous infusion of 40 miligrams of 0.5% lidocaine in combination with 1 milligram ketorolac plus 1 cc 0.09% normal saline. Intervention 2: Second grou

Treatment - Drugs

Placebo

First group of intervention: intravenous infusion of 40 miligrams of 0.5% lidocaine in combination with 1 milligram ketorolac plus 1 cc 0.09% normal saline

Second group of intervention: intravenous infusion of 40 milligrams of 0.5% lidocaine plus 2 milligrams ketorolac

Control group: intravenous infusion of 40 milligrams of 0.5% lidocaine in combination with 2 cc 0.09% normal saline(placebo)

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Main inclusion criteria: age limitation 20-50 years; plating candidates of forearm fracture with ASA PS I and II. Main exclusion criteria: positive history of sensitivity to NSAIDs; history of asthma, nasal polyp, bronchospasm or angioedema; history of bleeding of gastric ulcer; medium to severe renal failure; pregnant women; addiction; multiple fractures.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain after tourniquet deflation. Timepoint: half of houre,two houres, four houres, six houres, 12 houres and 24 houres after tourniquet deflation. Method of measurement: VAS Criteria.;Pain during tourniquet closure. Timepoint: 5, 10, 15, 20 and 30 minutes after infusion. Method of measurement: VAS Criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Kadkhudaei

Zahedan University of Medical Sciences

l.kadkhudaei@zaums.ac.ir+98 54 3329 5580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026