Skip to content

Effect of Fenugreek in the treatment of diabetes

Effect of fenugreek seeds on inflammatory and antioxidant factors in patients with type 2 diabetes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017021232294N2
Enrollment
48
Registered
2017-03-27
Start date
2017-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: Control group: no action. Intervention 2: Intervention group: 15 grams of powdered fenugreek seeds in doses of 5 grams three times a day between meals, dissolved in water for 8 weeks.
Treatment - Other
Control group: no action

Sponsors

School of Nutrition and Food Sciences, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: voluntary participation; At least 1 year and a maximum of 10 years diabetes history and observing at least 6 months diabetic diet; taking oral drugs lowering blood glucose to control diabetes; 18 to 65 years old; Lack of pregnancy and lactation; Not having certain diseases (liver, kidney, heart, thyroid, rheumatoid, respiratory, metabolic, gastrointestinal, malignancy, allergic diseases); no need for insulin; not using dietary, vitamin and mineral supplements, at least three months before the study; not hormone therapy; no smoking; no using other medicinal plants routinely, at least 3 months prior to the study exclusion criteria: unwillingness to continue; developing specific diseases (liver, kidney, heart, thyroid, rheumatoid, respiratory, metabolic, gastrointestinal, malignancy, allergic diseases) during the study; starting pregnancy and lactation; starting insulin therapy; starting using dietary, vitamin and mineral supplements; change in the dose of oral blood glucose lowering drugs; Change in the physical activity during the study; start taking other medicinal plants routinely

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Tumor necrosis factor-a. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level by ELISA kit.;Total antioxidant capacity. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level by ELISA kit.;Interleukin-6. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level by ELISA kit.;Glutathione peroxidase. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level by ELISA kit.;Superoxide dismutase. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level by ELISA kit.;High-sensitivity C-reactive protein. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level by ELISA kit.;Fasting blood glucose. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level.;2-hour post prandial glucose. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of serum level.;Hemoglobin A1C. Timepoint: before intervention and 2 months after starting the intervention. Method of measurement: Measurement of blood level.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRahele Tavakoly

School of Nutrition and Food Sciences, Isfahan University of Medical Sciences

tavakkoli.rahele@yahoo.com+98 31 3792 3151

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026