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The Comparison of Sedation Induction Time of Haloperidol, Perphenazine, Chlorpromazine, Promethazine, Trifluoperazine on Aggressive Patients

The Comparison of Sedation Induction Time of Haloperidol, Perphenazine, Chlorpromazine, Promethazine, Trifluoperazine on Aggressive Patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170212032528N2
Enrollment
76
Registered
2018-12-10
Start date
2016-06-21
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Aggression. Unspecified mood [affective] disorder

Interventions

Intervention 1: Intervention Group 1: Injection of 5mg Haloperidol (Exir, Tehran, Iran). Intervention 2: Intervention Group 2: Injection of 50 mg Chlorpromazine (TehranChemie, Tehran, Iran). Intervent

Sponsors

Vice chancellor for research of Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Age>18 Years Have consent to enter the study by patient accompaniment Have no Contraindication for Interventional Drug (For Instance Muscle Rigidity and Neuroleptic Malignant Syndrome) Having Verbal Violence in the Time of First Visit Having Physical Violence in the Time of First Visit

Exclusion criteria

Exclusion criteria: Patient Family's Refuse for Collaboration After the First Agreement

Design outcomes

Primary

MeasureTime frame
Sedation Velocity. Timepoint: During the Intervention and 2 hours later after intervention. Method of measurement: Signs and Time of Aggression Registered list.

Secondary

MeasureTime frame
Adverse Effects of Sedative Drug. Timepoint: One Hour after Injection. Method of measurement: Drug side effects check list.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDelaram Eghtesadi, M.D

Isfahan University of Medical Sciences

Bsrc@med.mui.ac.ir+98 31 3222 2127

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026