Condition 1: Polycystic Ovarian Syndrome. Condition 2: Female Infertility. Polycystic ovarian syndrome Female infertility associated with male factors
Conditions
Interventions
Intervention 1: Intervention group: 3mg of Melatonin tablet. Intervention 2: Control group: Placebo of Melatonin tablet.
Treatment - Drugs
Placebo
Intervention group: 3mg of Melatonin tablet
Control group: Placebo of Melatonin tablet
Sponsors
Tehran University of Medical Sciences, Deputy of Research, School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria 1- Age from 20 to 35 years 2- Wife's normal spermogram 3- Normal Hysterosalpingography 4- Has normal Rotterdam diagnostic criteria for PCO 5- No underlying conditions such as thyroid, diabetes, hyperprolactinemia Exclusion criteria 1- unsolicited ovarian response 2- Hyper stimulation syndrome 3- Non-referred
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fertility rate in both intervention and control groups. Timepoint: Two weeks after IUI surgery. Method of measurement: Using laboratory kits to measure BHCG in the blood. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determining the thickness of the endometrium per day of IUI. Timepoint: Once during IUI. Method of measurement: Transvaginal ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Fatane Mokhtari
Tehran University of Medical Sciences
Outcome results
None listed