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Glucose containing crystalloid effect on hemodynamic status during cesarean section

Effect of glucose containing crystalloid infusion on maternal hemodynamic status during spinal anesthesia for cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201702077013N17
Enrollment
90
Registered
2017-02-18
Start date
2017-02-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes during cesarean section by epidural analgesia. Complication of anaesthesia during labour and delivery, unspecified

Interventions

Intervention 1: Control group: Placebo group solution will be prepared by adding 20 ml distilled water to 1-liter ringer serum. During administration of epidural analgesia, 8 ml/kg body weight bullous
Treatment - Other
Control group: Placebo group solution will be prepared by adding 20 ml distilled water to 1-liter ringer serum. During administration of epidural analgesia, 8 ml/kg body weight bullous intravenous flu
Study group: Study group solution will be prepared by adding 20 ml glucose (10 gram) glucose to 1-liter ringer serum. During administration of epidural analgesia, 8 ml/kg body weight bullous intraveno

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: class I in American society of anesthesiology; aged between 18-40 years old; term pregnancy; singleton pregnancy; candidate for elective cesarean section; candidate for epidural analgesia. Exclusion criteria: emergent cesarean section; systemic diseases (renal, cardiac, pulmonary, hepatic, neuromuscular and etc.); mental disorders; body mass index more than 30 kilograms per meter square; history of glucose intolerance; consumption of drugs effecting glucose metabolism; allergy to bupivacaine; contraindications for epidural analgesia; fetal complication (asphyxia, meconium stained amniotic fluid).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: each 2 minutes till fetal birth, then each 5 minutes till end of the operation. Method of measurement: measuring patients blood pressure.;Dyastolic blood pressure. Timepoint: each 2 minutes till fetal birth, then each 5 minutes till end of the operation. Method of measurement: measuring patients blood pressure.;Mean arterial pressure. Timepoint: each 2 minutes till fetal birth, then each 5 minutes till end of the operation. Method of measurement: calculating using mean arterial pressure formula.;Heart rate. Timepoint: each 2 minutes till fetal birth, then each 5 minutes till end of the operation. Method of measurement: Using pulseoxymetery.

Secondary

MeasureTime frame
Maternal blood glucose. Timepoint: before operation, after operation. Method of measurement: using blood sugar glucometer.;Measurement the dosage of vasopressor agents used. Timepoint: after operation. Method of measurement: measuring dosage of vasopressor agents used.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Simin Atashkhoyi

Tabriz University of Medical Sciences

atashkhoii@tbzmed.ac.ir+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026