The effect of Melatonin on remission in patients with pulmonary contusion

Evaluation of the effect of melatonin on remission in patients with pulmonary contusion due to trauma

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170206032419N5

Enrollment

150

Registered

2018-12-26

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary contusion. Contusion of lung

Interventions

Intervention 1: Intervention group are receiving melatonin with dose of 0.1 mg / kg. Intervention 2: Control group: Receive serum therapy and oxygen therapy.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with pulmonary contusion due to Blunt trauma Patients with informed consent

Exclusion criteria

Exclusion criteria: Pregnant or lactating women Patients with penetrating trauma Drug interactions with Melatonin Patients with digestive disorders

Design outcomes

Primary

Measure	Time frame
The Serum NO level. Timepoint: After administration of Melatonin. Method of measurement: Total antioxidant capacity assay kit.	—

Secondary

Measure	Time frame
Total oxidant capacity. Timepoint: After administration of Melatonin. Method of measurement: Total antioxidant capacity assay kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Sadat Mojabi

Qazvin University of Medical Sciences

Mary.mojabi@yahoo.com+98 28 3333 5800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026