The effects of nebulized salbutamol on transient tachypnea of neonates treatment.

The effects of nebulized salbutamol on Transient Tachypnea of Neonates (TTN) treatment in Neonatal Intensive Care Unit (NICU) of Rajaei hospital of Tonekabon.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170201032346N4

Enrollment

Registered

2020-11-28

Start date

2016-12-21

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transient tachypnea of neonates. Transient tachypnea of newborn

Interventions

Intervention 1: Intervention group: Inhalational 15mg/kg salbutamol (Ventolin Respiratory Solution, salbutamol sulfate 5 mg/mL) in 2 mL of 0.9 saline in a single dose is administered by nebulizer. In

Eligibility

Sex/Gender

All

Age

No minimum to 3 Days

Inclusion criteria

Inclusion criteria: Diagnosis of TTN before 6 hour of birth according to Rawling and Smith criteria.

Exclusion criteria

Exclusion criteria: Diagnosis of respiratory distress syndrome Presence of end-organ dysfunction Sepsis Diagnosis

Design outcomes

Primary

Measure	Time frame
TTN score. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: According to clinical severity criteria of transient tachypnea of neonates, disease is scored from 0 to 13. Higher score indicate more severe disease. The criteria includes: Expiratory grunting: None=0, Intermittent=1, Continuous=2. Supraclavicular Retraction: None=0, Mild=1, Moderate=2, Severe=3. Subcostal Retraction: None=0, Mild=1, Moderate=2, Severe=3. Cyanosis: None=0, Acral=1, Central=2. Nasal Flaring: None=0, Mild=1, Moderate=2, Severe=3.;Heart rate. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Cardiac Monitoring. Beats per minutes.;Respiratory rate. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Cardiac Monitoring. cycle per minutes.;O2 Saturation. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Pulseoximeter, Percentage.;Body temperature. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Thermometer. degree of Celsius.	—

Measure

Time frame

TTN score. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: According to clinical severity criteria of transient tachypnea of neonates, disease is scored from 0 to 13. Higher score indicate more severe disease. The criteria includes: Expiratory grunting: None=0, Intermittent=1, Continuous=2. Supraclavicular Retraction: None=0, Mild=1, Moderate=2, Severe=3. Subcostal Retraction: None=0, Mild=1, Moderate=2, Severe=3. Cyanosis: None=0, Acral=1, Central=2. Nasal Flaring: None=0, Mild=1, Moderate=2, Severe=3.;Heart rate. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Cardiac Monitoring. Beats per minutes.;Respiratory rate. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Cardiac Monitoring. cycle per minutes.;O2 Saturation. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Pulseoximeter, Percentage.;Body temperature. Timepoint: 20 minutes and 6 hours after treatment. Method of measurement: Thermometer. degree of Celsius.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFirouzi Hossein

Ramsar Campus, Mazandaran University of Medical Sciences

firoozihosein@mazums.ac.ir+1 155230181

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026