lumbar discopathy. Nerve root and plexus compressions in intervertebral disc disorders
Conditions
Interventions
Intervention 1: Intervention A: Tablet Melatonin 3 mg, 1 hour before surgery. Intervention 2: Intervention B: Tablet Melatonin 5 mg, 1 hour before surgery. Intervention 3: Intervention C: Tablet Melat
Treatment - Drugs
Placebo
Intervention A: Tablet Melatonin 3 mg, 1 hour before surgery
Intervention B: Tablet Melatonin 5 mg, 1 hour before surgery
Intervention C: Tablet Melatonin 10 mg, 1 hour before surgery
Control: Tablet Placebo, 1 hour before surgery
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: Confirmation of the diagnosis using physical examination, computed tomography (CT) scan and magnetic resonance imaging (MRI) patient agreement and informed written consent candidate of elective discectomy surgery age 35 to 70 years
Exclusion criteria
Exclusion criteria: consumption of opium 24 hour before surgery drug or alcohol abuse any unusual complication during surgery Patients' unwillingness at any time to continue participation in this study emergency discectomy surgery involvement of more than two lumbar discs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain after disc surgery. Timepoint: 1, 6, 12, 24 hour after surgery. Method of measurement: VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pruritus,Nausea and vomiting,Satisfaction of pain cotrol. Timepoint: 1,6,12,24 hour after surgery. Method of measurement: VAS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Reza Habibi
Sari University of Medical Sciences
Outcome results
None listed