Heart disease. Atherosclerotic cardiovascular disease, so described
Conditions
Interventions
Intervention 1: In this study, in the intervention group, patients with BMI over 25, obtained number from lean body mass will be multiplied by 2.4 and according to it pump flow will be arranged in car
Prevention
Treatment - Drugs
In this study, in the intervention group, patients with BMI over 25, obtained number from lean body mass will be multiplied by 2.4 and according to it pump flow will be arranged in cardiopulmonary byp
In this study, in the control group, patients with BMI over 25, obtained number from bodr sueface area will be multiplied by 2.4 and according to it pump flow will be arranged in cardiopulmonary byp
Sponsors
iran univercity of medical science
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1? Older than 18 years old 2? body mass index of between 25-35 3?open heart surgery with the use of cardiopulmonary bypass 4?not having disorder in kidney, lung, liver and cerebral and treatment-resistant hypertension 5, left ventricular ejection fraction more than 30% 6? patients with bilateral carotid artery stenosis greater than 50% or unilateral carotid stenosis greater than 70% 7,patients elective open heart surgery exclusion criteria from the study: 1 , any event that affect the normal process of open heart surgery include cardiopulmonary bypass requirement though surgery, persistent decline of blood pressure through cardiopulmonary bypass that not respond to Inotropic drug 2, death 3, aortic clamping time over 100 minutes 4, temperature reduction below 28 degree during operation for any reason the surgeon decide to catch a lower temperature than 28 degree
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| On mixed venous oxygen saturation. Timepoint: after anesthesia,during cardiiopulmonary bypass,after cardiopulmonary bypass. Method of measurement: content of each gas in arterial blood Under the pressure of eac gas.;Arterial blood lactate. Timepoint: after anesthesia,during cardiiopulmonary bypass,after cardiopulmonary bypass. Method of measurement: arterial blood sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| O2 consumption. Timepoint: during cardiopulmonary bypass. Method of measurement: content of each gas in venous blood Under the pressure of eac gas and pump flow rate. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParvin Vahid
Iran University of Medical Science
Outcome results
None listed