Haemorrhagic condition. Haemorrhagic condition, unspecified
Conditions
Interventions
Intervention 1: Intervention group:
After induction of anesthesia 1µ/ kg/min Dexmedtomidin be injected within 10 minutes, then dexmedtomidin infusion begins with 0.5 µ /kg/minute. Intervention 2: Con
Treatment - Drugs
Intervention group:
After induction of anesthesia 1µ/ kg/min Dexmedtomidin be injected within 10 minutes, then dexmedtomidin infusion begins with 0.5 µ /kg/minute.
Control group:
After induction of anesthesia, 50 ml normal saline as placebo administrated.
Sponsors
Vice-Chancellor for Research and Technology of Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients undergoing endoscopic sinus surgery; aged between 16 and 60 years; ASA class I and II. Exclusion Criteria: diabetes mellitus; coagulation disorders; kidney and liver dysfunction; cerebrovascular disease; cardiovascular disease; high blood pressure; asthma; chronic obstructive pulmonary disease; psychiatric patients; drug allergy; taking beta-blockers; heart rate of less than 55.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding. Timepoint: q 15 minute up to the end of anesthesia. Method of measurement: data collected from standard operting room monitoring systems. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomit. Timepoint: every 30 minutes during 2 hours recovery time. Method of measurement: VAS score.;Awakening time. Timepoint: after injection of neuromascular blockade. Method of measurement: time after reversal of neuromasculare blockade till eye opening on command. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSharzad Pooyan
Ahvaz Jundishapor University of Medical Sciences
Outcome results
None listed