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Determine and compare the effects of topical curcumin nanoparticles and chlorhexidine gel on gingival inflammation in chronic gingivitis

Determine and compare the effects of topical curcumin nanoparticles and chlorhexidine gel on gingival inflammation in chronic gingivitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017012832231N1
Enrollment
40
Registered
2017-02-07
Start date
2016-11-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingivitis. Chronic gingivitis

Interventions

Intervention 1: Nano Gel topical curcumin At a dose of 1% twice a day for 1 minute. Intervention 2: Chlorhexidine 0.2% Twice daily mouthwash for 30 seconds.
Treatment - Drugs
Nano Gel topical curcumin At a dose of 1% twice a day for 1 minute
Chlorhexidine 0.2% Twice daily mouthwash for 30 seconds

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor
Mashhad University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria:A public health; Being without antibiotic prophylaxis; Non-use of anti-inflammatory substances within six weeks ago and at the time of check; Do not use medications such as antihistamines, antidepressants or analgesics within six weeks ago at the time of review; none pregnant Exclusion criteria:Pregnant or lactating mothers; Systemic Disease; Allergy to any drug in medical history, especially of turmeric periodontitis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Plaque index. Timepoint: After SRP , 2 weeks later and a month later. Method of measurement: Eye determining PI.;GBI. Timepoint: After SRP , 2 weeks later and a month later. Method of measurement: Eye determining GBI.;BOP. Timepoint: After SRP , 2 weeks later and a month later. Method of measurement: Eye determining BOP by Periodontal Probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Kazem Fatemi

Mashhad University of Medical Sciences

fatemik@mums.ac.ir+98 51 3806 7224

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026