Uterine leiomyomas. Leiomyoma of uterus -Leiomyoma of uterus, unspecified
Conditions
Interventions
Intervention 1: The women in Intervention group will receive 400 mg oral mullein capsules twice a day for two months. Intervention 2: women in control group will receive 400 mg placebo capsules (conta
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Willingness to participate in the study, having a literate and able to answer the questions, women of reproductive age 18-50 years with asymptomatic uterine leiomyomas that confirmed by abdominal ultrasound (at least one leiomyoma largest than 2.5 cm), women with normal menstruation (35-21 days).
Exclusion criteria
Exclusion criteria: Exclusion criteria: Pregnant and lactating women, desire to become pregnant during the next three months, uterine leiomyoma in size more than 12 cm, the size of the uterine leiomyoma equal or more than 20 weeks of gestation, anemia requiring treatment, history of chronic diseases (such as heart disease, thyroid, etc.) and concurrent use of other medications or herbal remedies, history of previous surgery such as myomectomy, use the OCP or other methods of hormone therapy during the last three months, presence of a hormonal IUD, known diseases of the genital tract, Allergy to treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size of Uterine Liomyoma. Timepoint: before intervention and 2 month after intervention. Method of measurement: Sonography study.;Menstrual bleeding loss. Timepoint: beefore intervention and 4 ,8 weeks after intervention. Method of measurement: Pictorial Blood Loss Assessment Chart (PBAC). | — |
Secondary
| Measure | Time frame |
|---|---|
| Haemoglobin. Timepoint: before intervention and 2 months after intervention. Method of measurement: blood exam.;Size of uterine. Timepoint: before intervention and 2 months after intervention. Method of measurement: Sonography study.;Side events. Timepoint: two months after intervention. Method of measurement: Checklist of side events.;Satisfaction with treatment received. Timepoint: two months after intervention. Method of measurement: Checklist of Satisfaction with treatment received. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNafiseh Ghassab Abdollahi
Tabriz University of Medical Sciences
Outcome results
None listed