Oral Magnesium Therapy in Periodic Limb Movement Syndrome

Evaluation of Oral Magnesium Therapy for Periodic Limb Movement Syndrome: a Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170128032249N2

Enrollment

Registered

2019-06-16

Start date

2019-09-23

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodic limb movements in sleep. Periodic limb movement disorder

Interventions

Intervention 1: Intervention group: a 250 mg magnesium tablet will prescribe once a day for 4 weeks after a meal. Intervention 2: Control group: a placebo tablet will prescribe once a day for 4 weeks

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: periodic limb movements in polysomnography

Exclusion criteria

Exclusion criteria: decrease in ferritin level increase in blood urea nitrogen increase in cratinine pregnancy iron deficiency anemia

Design outcomes

Primary

Measure	Time frame
Periodic limb movements in sleep. Timepoint: At the beginning of the study and 28 days after the start of oral magnesium. Method of measurement: polysomnography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Banafsheh Alemohammad

Tehran University of Medical Sciences

alemohammadz@sina.tums.ac.ir+98 21 5567 7333

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026