Skip to content

The effect of administration of Selenium in preventing atrial fibrillation after Coronary Artery Bypass Graft (CABG) Surgery

Effect of Selenium on preventing atrial fibrillation after Coronary Artery Bypass Graft (CABG) Surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201701252883N5
Enrollment
150
Registered
2017-03-24
Start date
2016-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation. Atrial fibrillation and flutter

Interventions

Intervention 1: Intervention group: 2000 µg Selenium supplementation in the prime solution during cardiopulmonary bypass. Intervention 2: Control group: Normal saline in the prime solution during card
Treatment - Drugs
Placebo
Intervention group: 2000 µg Selenium supplementation in the prime solution during cardiopulmonary bypass
Control group: Normal saline in the prime solution during cardiopulmonary bypass

Sponsors

Vice chancellor for research,Mazandaran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidate for CABG; non-emergency surgery; use of cardiopulmonary bypass pump during surgery; no history of cardiac tachyarrhythmia before surgery; hemodynamic stability ( heart beat 50-110, MAP>50); between 35 to 75 years old. Exclusion criteria: Heart failure (EF 0.1 µg/kg/min dopamine and dobutamine > 10µg/kg/min).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Atrial Fibrillation. Timepoint: Immediately after surgery and on the first,second and third day after operation and transferring to ICU. Method of measurement: Saadat Monitoring Devices.

Secondary

MeasureTime frame
Other arrhythmias. Timepoint: Immediately after the surgery and on the first, second or third day after operation and transferring to ICU. Method of measurement: saadat monitoring devices.;Hs-CRP serum levels. Timepoint: Befor the surgery,after bypass and on the first day hospitalization in ICU. Method of measurement: VIDZS devices And VIDZS Kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Enayati, MD

Mazandaran University of Medical Sciences

enayati@mazums.ac.ir+98 11 3332 4002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026