Obsessive-compulsive disorder. Obsessive-compulsive disorder
Conditions
Interventions
Intervention 1: Tropisetrone capsul 5mg daily and Fluvoxamine tablet 100mg daily for 4 first weeks and 2 per day for upcoming weeks. Oral ingestion is route of prescription. Intervention 2: Placebo ca
Treatment - Drugs
Tropisetrone capsul 5mg daily and Fluvoxamine tablet 100mg daily for 4 first weeks and 2 per day for upcoming weeks. Oral ingestion is route of prescription.
Placebo capsul daily and Fluvoxamine tablet 100mg daily for 4 first weeks and 2 per day for upcoming weeks. Oral ingestion is route of prescription.
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients who meet DSM-IV-TR criterion for OCD and they achieve more than 21 for Yale-Brown Obsessive Compulsive Scale are suitable for study. They should be 18-60 years old and sign consent form. they should not be treated by any psychiatric interventions for 6 weeks ago. If they show any other mental important conditions or suicidal thoughts, neurological deficits, exclude from study. They will evaluate for cardiac, liver, kidney, pregnancy, lactation and mental retardation before entrance and any mentioned conditions will cause exclusion from study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of obsessive-compulsive disorder. Timepoint: Weeks: 0, 4, 8 and 10. Method of measurement: Yale-Brown Obsessive Compulsive Scale(YBOCS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Weeks: 0, 4, 8 and 10. Method of measurement: Checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Reza Shalbafan
Iran University of Medical Sciences
Outcome results
None listed