Labor pain relief with Entonox

Comparison of analgesic effect of inhaling Entonox alone and in combination with dexamethasone in labor

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017012323559N8

Enrollment

Registered

2017-03-24

Start date

2017-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain. Delivery

Interventions

Intervention 1: Face mask of entonox at the beginning of uterine contractions and continue deep inspirations in times when there is pain and cramps and intravenous placebo (Distilled water, 2 cc, Iran

Treatment - Drugs

Face mask of entonox at the beginning of uterine contractions and continue deep inspirations in times when there is pain and cramps and intravenous placebo (Distilled water, 2 cc, Irandaroo Co., once)

Face mask of entonox at the beginning of uterine contractions and continue deep inspirations in times when there is pain and cramps and 8mg intravenous dexamethasone (2 cc, IrandarooCo., once)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: Over 37 weeks pregnancy, first or second pregnancy, singleton. Exclusion criteria: Malpresentation of fetus? Macrosomia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before analgesic administrations and two times (30 and 60 min) after intervention. Method of measurement: Visual analog scale.	—

Secondary

Measure	Time frame
Apgar. Timepoint: 1 and 5 minutes after birth. Method of measurement: Apgar test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fateme Hashemi

Ardabil University of Medical Sciences

Fatemehhashemigyn1392@ yahoo.com+98 45 3324 8888

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026