Drug holiday method on sexual function in men treated with selective serotonin reuptake inhibitors

The effectiveness of drug holiday method on sexual function in men treated with selective serotonin reuptake inhibitors other than fluoxetine: a randomized clinical trial compared with control group

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170123032145N6

Enrollment

Registered

2021-10-25

Start date

2021-11-06

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual side effect with SSRIs. Other psychoactive substance use, unspecified with psychoactive substance-induced sexual dysfunction

Interventions

Intervention 1: Intervention group: Drug holiday group won`t use the SSRI in two days in every week. Intervention 2: Control group: Control group continues the medication without any change in type an

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Married lived with wife In maintenance phase of treatment with a SSRI Suffering from sexual side effect

Exclusion criteria

Exclusion criteria: Sexual dysfunction before starting the medication, substance dependence and taking another medication with established sexual side effect currently

Design outcomes

Primary

Measure	Time frame
Sexual function. Timepoint: Weeks: 0, 4, 8. Method of measurement: Male Sexual Health Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammadreza Shalbafan

Iran University of Medical Sciences

shalbafan.mr@iums.ac.ir+98 21 6655 1665

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026