Condition 1: Prevention of postoperative shivering. Condition 2: Postoperative shivering in general anaesthesia. complication of surgical and medical care, unspecified complication of surgical and medical care, unspecified
Conditions
Interventions
Intervention 1: Group A will receive dexamethasone 0.15 mg/kg intravenously. Intervention 2: Group B will receive ketamine 0.5 mg/kg intravenously. Intervention 3: Group C will receive pethidine 0.5
Prevention
Placebo
Group A will receive dexamethasone 0.15 mg/kg intravenously.
Group B will receive ketamine 0.5 mg/kg intravenously.
Group C will receive pethidine 0.5 mg/kg intranenously.
Group D will receive normal saline 2 ml intravenously.
Sponsors
Vice Chancellor for Research of Gonabad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: The patients must: be between 20-60 years old; undergo general anaesthesia; be willing to participate in the study; filling in the informed consent form; not have cardiac nor pulmonary diseases; not have thyroid dysfunction; be healthy; not be allergic to the prescribed medicines; not suffer from Parkinson’s disease; dysautonomia nor rhynod syndrome; not drink alcohol; not use vasodilator; and not suffer from neurologic nor psychological disorders. Exclusion Criteria: Transfusion during surgery; malignant Hyperthermia; having central temperature less than 5.36 degrees centigrade or higher than 38 during operation; and the occurrence of any kind of clinical outcome or condition that prevents the patient’s postoperative evaluation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shivering. Timepoint: Postoperative. Method of measurement: Checklist.;Shivering after general anaesthesia. Timepoint: 10 minutes. Method of measurement: Observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Postoperative. Method of measurement: Checklist.;Hallusination. Timepoint: Postoperative. Method of measurement: Checklist.;Diastolic blood pressure. Timepoint: Every 15 minutes before anaesthesia induction until one hour after the end of operation. Method of measurement: Sphygmomanometer.;Systolic blood pressure. Timepoint: Every 15 minutes before anaesthesia induction until one hour after the end of operation. Method of measurement: Sphygmomanometer.;Delirium. Timepoint: Postoperative. Method of measurement: Checklist.;Nausea, Vomiting. Timepoint: Postoperative. Method of measurement: Checklist.;Body temperature. Timepoint: Every 15 minutes before anaesthesia induction until one hour after the end of operation. Method of measurement: Thermometer.;Environment tempreture. Timepoint: Every 15 minutes before anaesthesia induction until one hour after the end of operation. Method of measurement: Thermometer.;Heartbeat. Timepoint: Every 15 minutes before anaesthesia induction until one hour after the end of operation. Method of measurement: Pulse Oximeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSepideh Sedaghati Ansari
Gonabad University of Medical Sciences
Outcome results
None listed