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Survey the effect of saffron on asthma

Survey the effect of saffron supplementation on the antibody titer to heat-shock protein (HSP) 70, hsCRP and spirometry test in patients with moderate persistent allergic asthma

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017012132081N2
Enrollment
86
Registered
2017-04-03
Start date
2017-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moderate persistent allergic asthma.

Interventions

Intervention 1: Saffron consumer group which receiving 100 mg of saffron per day in capsule form (two 50 mg capsule per day). Drug producing center: growth center of Ahvaz Jundishapur University of m
Treatment - Drugs
Placebo
Saffron consumer group which receiving 100 mg of saffron per day in capsule form (two 50 mg capsule per day). Drug producing center: growth center of Ahvaz Jundishapur University of medical sciences.
Placebo consumer group: consumption two capsules per day which containing starch. Drug producing center: growth center of Ahvaz Jundishapur University of medical sciences. Duration of drug consumptio

Sponsors

Vice Chancellor for research of Ahvaz Jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18 to 65 years old, moderate persistent allergic asthma (FEV1 between 40 to 60 percent) according to the physician and normal BMI (up to 27). Inclusion criteria dos not belong to the particular gender and include male and females. Exclusion criteria include smoking, diabetes, pregnancy and lactation, autoimmune disease, malignancies, gastrointestinal, liver and kidney disease, pneumonia and other pulmonary disease and Not wanting to continue cooperation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Antibody titers to heat shock protein 70. Timepoint: Before and two months after intervention. Method of measurement: according to the Laboratory Measurement-ng/ml.;FEV1, FVC, FEV1/FVC. Timepoint: Before and two months after intervention. Method of measurement: According to the results of the spirometer-scale:percent.

Secondary

MeasureTime frame
HsCRP. Timepoint: Before and two months after intervention. Method of measurement: according to the laboratory measurement-mg/dl.;Lipid profile. Timepoint: Before and two months after intervention. Method of measurement: according to the laboratory measurement-mg/dl.;Blood presure. Timepoint: Before and two months after intervention. Method of measurement: according to the results of Sphygmomanometer-mmhg.;Clinical variables and the patient's general status. Timepoint: Before and two months after intervention. Method of measurement: according to the Questionnaires completed by physician superspecialty.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzie Zilaee

Department of nutrition, paramedicine school

zilaee.m@ajums.ac.ir+98 61 3336 7543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 22, 2026