Effect of Desmopressin on Bleeding During The Nose Job

The Effect Of Desmopressin Intraoperatively On Hemorrhage During The Rhinoplasty

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170120032069N7

Enrollment

Registered

2020-06-20

Start date

2020-07-22

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty and haemorrhage during the surgery.

Interventions

Intervention 1: Intervention group: Thirty minutes before the surgery, 500 ml of normal saline containing 0.1µgr / kg of Desmopressin is injected. Intervention 2: Control group: Thirty minutes before

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Volunteers with no age limit who undergo the Rhinoplasty

Exclusion criteria

Exclusion criteria: Cardiovascular disease Bleeding disorders High blood pressure Allergy to Desmopressin History of cerebrovascular attack Seizure

Design outcomes

Primary

Measure	Time frame
Bleeding during rhinoplasty surgery. Timepoint: Measuring the amount of bleeding at the end of surgery. Method of measurement: The sucker bottle which is calibrated measures bleeding loss.;View of surgeon on operating field. Timepoint: Measuring surgeon satisfaction at the end of surger. Method of measurement: based on the FROMME-BOEZAART Scale.;The time of surgery. Timepoint: Measuring the time of surgery at the end of surgery. Method of measurement: Duration of surgery from the begining to the end of the surgery.	—

Measure

Time frame

Bleeding during rhinoplasty surgery. Timepoint: Measuring the amount of bleeding at the end of surgery. Method of measurement: The sucker bottle which is calibrated measures bleeding loss.;View of surgeon on operating field. Timepoint: Measuring surgeon satisfaction at the end of surger. Method of measurement: based on the FROMME-BOEZAART Scale.;The time of surgery. Timepoint: Measuring the time of surgery at the end of surgery. Method of measurement: Duration of surgery from the begining to the end of the surgery.

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Secondary

Measure	Time frame
Bleeding will be measured by the surgeon based on the FROMME-BOEZAART Scale. Timepoint: During the surgery. Method of measurement: Based on this scale, there are five grades in which the surgeon during the surgery scores the bleeding. Grade 0: No bleeding (cadaveric conditions); grade 1: Slight bleeding, no suctioning required; grade 2: Slight bleeding, occasional suctioning required; grade 3: Slight bleeding, frequent suctioning required; bleeding threatens surgical field a few seconds after suction is removed; grade 4:Moderate bleeding, frequent suctioning required, and bleeding threatens surgical field directly after suction is removed; grade 5:Severe bleeding, constant suctioning required; bleeding appears faster than can be removed by suction; surgical field severely threatened and surgery usually not possible.	—

Measure

Time frame

Bleeding will be measured by the surgeon based on the FROMME-BOEZAART Scale. Timepoint: During the surgery. Method of measurement: Based on this scale, there are five grades in which the surgeon during the surgery scores the bleeding. Grade 0: No bleeding (cadaveric conditions); grade 1: Slight bleeding, no suctioning required; grade 2: Slight bleeding, occasional suctioning required; grade 3: Slight bleeding, frequent suctioning required; bleeding threatens surgical field a few seconds after suction is removed; grade 4:Moderate bleeding, frequent suctioning required, and bleeding threatens surgical field directly after suction is removed; grade 5:Severe bleeding, constant suctioning required; bleeding appears faster than can be removed by suction; surgical field severely threatened and surgery usually not possible.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Amir Hossein Ghabasiah

Tehran University of Medical Sciences

AH.ghabasiah@gmail.com+98 21 6671 2549

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026