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Desmopressin effects on bleeding after functional endoscopic sinus surgery on patients with chronic rhinosinusitis with and without polyposis

desmopressin effects on bleeding after functional endoscopic sinus surgery on patients with chronic rhinosinusitis with and without polyposis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170120032069N5
Enrollment
19
Registered
2019-11-10
Start date
2019-03-21
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic rhinosinositis with and without polyposis. chronic Rhinosinositis, polyposis, Desmopressin, FESS

Interventions

Intervention 1: Intervention group: Intervention group: 100mg normal saline containing 0.1µgr / kg desmopressin will be injected 1 min before surgery in case group. If the surgeon is dissatisfied from

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with chronic rhinosinusitis in the age group of 15-60 years old No heart disease without Background coagulation disorders Without high blood pressure No history of previous FESS surgery

Exclusion criteria

Exclusion criteria: If patients are not satisfied with entering the project

Design outcomes

Primary

MeasureTime frame
Reduce bleeding during FESS surgery - better view of surgeon on operating field -- Reduce the time of surgery. Timepoint: Measuring the amount of bleeding at the end of surgery .... Measuring surgeon satisfaction at the end of surgery .... Measuring the time of surgery at the end of surgery. Method of measurement: Calibrated container to measure the amount of bleeding. A numerical questionnaire is used to measure the surgeon's satisfaction .measure the time of operation by clock.

Secondary

MeasureTime frame
Reduce the need for postoperative blood transfusions .... Reduce the need for intraoperative anesthesia. Timepoint: Both outcomes are measured at the end of surgery. Method of measurement: The rate of hemoglobin loss at the end of surgery and the amount of anesthetic drugs used during surgery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJawad Hosseini

Tehran University of Medical Sciences

jawadhosseini.md@gmail.com+98 21 6670 6106

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026