Effect of energy-matched continuous vs interval training in type-2 diabetes

Comparison of the effect of energy-matched continuous vs high-intensity interval training with weight-loss diet on metabolic indices and arterial stiffness in patients with type-2 diabetes

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170120032066N5

Enrollment

Registered

2023-05-31

Start date

2023-06-20

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type-2 diabetes. Type 2 diabetes mellitus

Interventions

Intervention 1: Intervention group: continuous exercise training and calorie restriction over 12 weeks. Intervention 2: Intervention group: interval exercise training and calorie restriction over 12 w

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: History of type-2 diabetes over 5 years Glycosylated hemoglobin (Hb1Ac) over 6.5% Fasting blood glucose over 126 mg/dl Inactive lifestyle Body mass index over 25 kg/m2

Exclusion criteria

Exclusion criteria: Having weight-loss diet Severe diabetic complications like foot ulcer Not permitted for exercise

Design outcomes

Primary

Measure	Time frame
Glycosylated hemoglobin (HbA1c). Timepoint: Measurement of glycosylated hemoglobin (HbA1c) before and after 12 weeks intervention. Method of measurement: Using a commercial kit through enzymatic method.;Systolic blood pressure. Timepoint: Measurement of systolic blood pressure before and after 12 weeks intervention. Method of measurement: Digital sphygmomanometer.;Cardio-ankle vascular index (CAVI). Timepoint: Measurement of Cardio-ankle vascular index (CAVI) before and after 12 weeks intervention. Method of measurement: Arterial stiffness assessment device VaSera VS-2000 (Fukuda Denshi, Japan).;Weight. Timepoint: Measurement of weight before and after 12 weeks intervention. Method of measurement: Using digital scale.;Body fat percentage. Timepoint: Measurement of body fat percentage before and after 12 weeks intervention. Method of measurement: Bioempedance method by body composition analyzer InBody230.	—

Measure

Time frame

Glycosylated hemoglobin (HbA1c). Timepoint: Measurement of glycosylated hemoglobin (HbA1c) before and after 12 weeks intervention. Method of measurement: Using a commercial kit through enzymatic method.;Systolic blood pressure. Timepoint: Measurement of systolic blood pressure before and after 12 weeks intervention. Method of measurement: Digital sphygmomanometer.;Cardio-ankle vascular index (CAVI). Timepoint: Measurement of Cardio-ankle vascular index (CAVI) before and after 12 weeks intervention. Method of measurement: Arterial stiffness assessment device VaSera VS-2000 (Fukuda Denshi, Japan).;Weight. Timepoint: Measurement of weight before and after 12 weeks intervention. Method of measurement: Using digital scale.;Body fat percentage. Timepoint: Measurement of body fat percentage before and after 12 weeks intervention. Method of measurement: Bioempedance method by body composition analyzer InBody230.

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Secondary

Measure	Time frame
Fasting blood glucose. Timepoint: Measurement of fasting blood glucose before and after 12 weeks intervention. Method of measurement: Enzymatic calorimetry.;2 hours postprandial glucose. Timepoint: Measurement of 2 hours postprandial glucose before and after 12 weeks intervention. Method of measurement: Enzymatic calorimetry.;Ankle-brachial index (ABI). Timepoint: Measurement of ankle-brachial index before and after 12 weeks intervention. Method of measurement: Arterial stiffness assessment device VaSera VS-2000 (Fukuda Denshi, Japan).	—

Measure

Time frame

Fasting blood glucose. Timepoint: Measurement of fasting blood glucose before and after 12 weeks intervention. Method of measurement: Enzymatic calorimetry.;2 hours postprandial glucose. Timepoint: Measurement of 2 hours postprandial glucose before and after 12 weeks intervention. Method of measurement: Enzymatic calorimetry.;Ankle-brachial index (ABI). Timepoint: Measurement of ankle-brachial index before and after 12 weeks intervention. Method of measurement: Arterial stiffness assessment device VaSera VS-2000 (Fukuda Denshi, Japan).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Gholami

Shahrood University of Technology

gholami-fa@shahroodut.ac.ir+98 23 3239 5900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026