knee osteo arthritis. Primary generalized (osteo)arthrosis
Conditions
Interventions
Intervention 1: control group:this group will consume of one tablet(1000mg placebo) one time a day after meals (lunch or breakfast) with weight loss diet for 12 weeks. tablets will produce from Karen
Treatment - Drugs
control group:this group will consume of one tablet(1000mg placebo) one time a day after meals (lunch or breakfast) with weight loss diet for 12 weeks. tablets will produce from Karen Company in Yazd.
intervention group:this group will consume of one tablet(1000mg L carnitine) one time a day after meals (lunch or breakfast) with weight loss diet for 12 weeks. tablets will produce from Karen Company
Sponsors
Vice Chancellor for research of School of Public Health, Shahid Sadoughi University of Medical Scien
Eligibility
Sex/Gender
Female
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: women? age between 45 to 70? Early detection of osteoarthritis? body mass index more than25? Lack of weight loss diets over the past three months? lack of participate in the intervention program the past three months Exclusion: heart disease? hypothyroidism? rheumatoid arthritis? hepatic disease?kidney disease and knee sergury
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: before intervention and 12 weeks after the intervention. Method of measurement: womac questionnaire.;Lipid profile(HDL, LDL, TG, Cho). Timepoint: before intervention and 12 weeks after the intervention. Method of measurement: with special kits.;CRP. Timepoint: before intervention and 12 weeks after the intervention. Method of measurement: with special kits.;Malondialdehyde. Timepoint: before intervention and 12 weeks after the intervention. Method of measurement: with special kits. | — |
Secondary
| Measure | Time frame |
|---|---|
| Waist, Hip circumference. Timepoint: before intervention and 12 weeks after the intervention. Method of measurement: meter.;Weight, fat mass, free fat mass. Timepoint: before intervention and 12 weeks after the intervention. Method of measurement: Omron digital Scale(BF11). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarnaz Baghban
School of Public Health, Shahid Sadoughi University of Medical Sciences,
Outcome results
None listed