Evaluation of the effect of very high dose atorvastatin on candidates for elective angioplasty

Prospective evaluation of the effect of statin recapture on high sensitive troponin T and NGAL in elective PCI patients referred to Tehran Heart Center

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017011831073N2

Enrollment

340

Registered

2017-05-02

Start date

2016-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction after elective stenting, contrast-induced nephropathy after elective stenting. Atherosclerotic heart disease, Old myocardial infarction

Interventions

Intervention: Atorvastatin, two 40 mg pills, 12 hours before PCI and 40 mg atorvastatin 2 hours befor PCI.

Treatment - Drugs

Intervention: Atorvastatin, two 40 mg pills, 12 hours before PCI and 40 mg atorvastatin 2 hours befor PCI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: candidate for Elective Percutaneous Coronary Intervention Exclusion criteria: High-Sensitivity Cardiac Troponin more than 24 NG/ML; Creatinine Clearance less than 30; Liver function test more than 3 times greater than normal; Ejection fraction less than 30 percent; Consumption of Amiodarone, Calcium channel blockers, Colchicine, and Digoxin

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum high sensitive troponin T. Timepoint: Before and within 24 hours after PCI. Method of measurement: ELISA.;Urine NGAL. Timepoint: Before and 2 hours after PCI. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Reza Lashkari

Tehran Heart Center

rzlashkari@gmail.com+98 21 8802 9721

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026