Early reduction in COVID-19 viral load. Other and unspecified parts of mouth
Conditions
Interventions
Intervention 1: Intervention group: In intervention group 1, patients will gargle and rinse 20 cc of 2% Povidone-iodine mouthwash in the mouth for 20 seconds. Intervention 2: Intervention group: In in
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosis of COVID-19 infection based on the opinion of the treating physician based on national guidelines Patients with mild to moderate disease
Exclusion criteria
Exclusion criteria: Patients with previous underlying oral disease Patients with inability to properly perform the mouthwash protocol Patients with thyroid disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early reduction of viral load in the mouth of COVID-19 patients. Timepoint: A sample of oropharyngeal swap will be taken from patients to check for viral load before intervention. Patients then use 20 cc of the appropriate mouthwash, based on the assigned group, which will be practically taught by the researcher on how to use it. After 30 minutes from the beginning of the intervention, the second sample of oropharyngeal swap will be determined to determine the virus load. After preparation, all samples will be placed in a tube containing a special medium for transmission (VTM) and will be transferred to the specialized reference laboratory COVID-19 of Hamadan University of Medical Sciences to determine the load of the virus by standard RT-PCR method. Method of measurement: A sample of an oropharyngeal swap will be taken from patients to check for viral load before intervention. After 30 minutes from the start of the intervention, a second oropharyngeal swap will be performed to determine the virus load. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Ali Heidari
Hamedan University of Medical Sciences
Outcome results
None listed