Depression. Depressive episode
Conditions
Interventions
Intervention 1: Intervention group1: Venlafaxine extended release (75 and 150 mg capsules) at a dose of 75 mg every 3 days starts and are added 37.5 mg.And based on the response and tolerance of side
Treatment - Drugs
Intervention group1: Venlafaxine extended release (75 and 150 mg capsules) at a dose of 75 mg every 3 days starts and are added 37.5 mg.And based on the response and tolerance of side effects, the dos
Intervention group2: Sertraline (100 and 50 mg tablets) starts once daily at a dose of 25 mg and gets added 25 mg every 3 days. And based on the response and tolerance of side effects will increase t
Sponsors
Vice chancellor for research Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age more than 18 years old;Fulfilled DSM IV TR criteria for major depressive disorder Baseline score 18 on the HDRS 17 Exclusion criteria: Lack of serious health problems including disease axis I and II comorbidity ; suicidal or killing thoughts ;pregnancy;Severe physical problems and unstable
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: before intervention, 2, 4, 6 weeks after treatment. Method of measurement: Hamilton Rating Scale for Depression. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHatam Boostani
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed