general anesthesia. Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
Conditions
Interventions
Intervention 1: In the first group (L group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weigh
Prevention
In the first group (L group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weight and remifentan
In the first group (H group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weight and remifentan
Sponsors
Vice chancellor for research, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patient candidated for elective laparascopic cholesystectomy; patient with ASA I or II; Lack of malignancy or seizures; Lack of auditory problem; BMI<35; Lack of heart, pulmonary, liver and kidney failure; Lack of uncontrolled systemic disease; Lack of addiction; Lack of chronic pain and/or with any analgesic drug.Exclusion criteria: Prolongation of action for more than three hours; Conversion of laparoscopic surgery to laparotomy; patient death.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate. Timepoint: during surgery, before and after that. Method of measurement: with pulse oxymeter device and according to beat per minute.;Need to analgesic drug. Timepoint: during 24 hours after surgery. Method of measurement: according to miligeram.;Amount of pain. Timepoint: in recovery and 8,16 and 24hours after surgery. Method of measurement: with using of VAS score.;Systolic and diastolic blood pressure. Timepoint: during surgery, before and after that. Method of measurement: Non-invasive barometer in mm Hg. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of nausea and vomitting. Timepoint: during 24 hours after surgery. Method of measurement: according to severity and score 0 to 3.;Duration of surgery. Timepoint: from start of surgery to start of recovery. Method of measurement: according to minute. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPoopak Rahimzadeh
Anesthesiology group of Iran University of Medical Science
Outcome results
None listed