The effect of capsules Nigella sativa seeds on the Premenstrual syndrome

The effect of capsules Nigella sativa seeds on the severity of symptoms of Premenstrual syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017011131881N1

Enrollment

Registered

2017-07-08

Start date

2017-01-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premenstrual syndrome. Premenstrual tension syndrome

Interventions

Intervention 1: Intervention group: Consumption of Nigella sativa seeds capsules to the 1,500 mg orally daily (3 capsules of 500 mg in 3 doses every 8 hours on a full stomach) from 7 days befor the s

Treatment - Drugs

Placebo

Intervention group: Consumption of Nigella sativa seeds capsules to the 1,500 mg orally daily (3 capsules of 500 mg in 3 doses every 8 hours on a full stomach) from 7 days befor the start of menstrua

Control group: Consumption of Placebo capsules to the 1,500 mg orally daily (3 capsules of 500 mg in 3 doses every 8 hours on a full stomach) from 7 days befor the start of menstrual bleeding to 3 da

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Student studying at Mashhad University of Medical Sciences and residing in a dormitory; Iranian and Muslim; Aged between 18 and 35; Regular & normal menstruation; And having premenstrual syndrome. Exclusion criteria: Pregnancy and lactation; Any history disorders; Any drug use; Smoking or drinking alcohol; Professional athlete; Depression and Anxiety and extreme stress; Use of traditional medicine methods to reduce the physical and behavioral symptoms of premenstrual syndrome ; BMI =30.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The severity of physical symptoms of Premenstrual syndrome. Timepoint: Daiy 2 cycles before the intervention. 2 cycles after the intervention. Method of measurement: Questionnaire COPE.	—

Secondary

Measure	Time frame
The Severity of behavioral symptoms of Premenstrual syndrome. Timepoint: Daiy 2 cycles before the intervention. 2 cycles after the intervention. Method of measurement: Questionnaire COPE.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamaneh Maskani

School of Nursing and Midwifery, Mashhad University of Medical Sciences

Maskanis931@mums.ac.ir+98 51 4464 1276

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026