Neutropenia. Neutropenia
Conditions
Interventions
Intervention 1: Intervention group 1: Group one will be treated with a daily dose of Filgrastim in the first period and Pegfilgrastim in the second, separated by a washout period of at least 30 days.
Treatment - Drugs
Intervention group 1: Group one will be treated with a daily dose of Filgrastim in the first period and Pegfilgrastim in the second, separated by a washout period of at least 30 days. The Filgrastim a
Intervention group 2: Group two will be treated with a daily dose of Pegfilgrastim in the first period and Filgrastim in the second, separated by a washout period of at least 30 days. The Filgrastim a
Control group: Third group will be received no medication.
Sponsors
Vice chancellor for research, Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 15 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Solid tumor confirmed by pathology; Children less than 15 years; Parental consent. Exclusion criteria: Severe infection; Use of Corticosteroid; Sensitivity to filgrastim or pegfilgrastim; Lack of parental consent to continue participating in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute Neutrophil Count. Timepoint: Before chemotherapy and the first, third, seventh and fourteenth day after Granulocyte Colony Stimulating Factor (GCSF) administration. Method of measurement: Laboratory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Aziz Eghbali
Amir-Kabir Hospital
Outcome results
None listed