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Effectiveness of transcranial Direct Current Stimulation (tDCS) in Obsessive-Compulsive Disorder patients

Comprative effectiveness of transcranial Direct Current Stimulation (tDCS) in both PreSMA and LOF inhibition and comparing them with placebo in reducing symptoms in nonresponsive OCD patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201701095138N3
Enrollment
51
Registered
2017-02-14
Start date
2016-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-Compulsive Disorder. These may take the form of ideas, mental images, or impulses to act, which are nearly always distressing to the subject. Sometimes the ideas are an indecisive, endless consideration of alternatives, associated with an inability to make trivial but necessa

Interventions

Intervention 1: 17 patient in 10 days and every day 20 min treated with tDCS that cathode on left orbitofrontal region and anode on contralateral region with intensity 2mA. Intervention 2: 17 patient
Treatment - Devices
Placebo
17 patient in 10 days and every day 20 min treated with tDCS that cathode on left orbitofrontal region and anode on contralateral region with intensity 2mA
17 patient in 10 days and every day 20 min treated with tDCS that cathode on left presupplementary motor area and anode on contralateral region with intensity 2mA
17 patient in 10 days and every day 20 second treated with tDCS that cathode on left orbitofrontal region and anode on contralateral region with intensity 2mA

Sponsors

Vice Chancellor for Research of Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Diagnosis of OCD according to DSMV ; Lack of response to treatment with 2 drugs with sufficient dose and time (equal 80 mg Fluoxetine) ; Only this diagnosis in axis I and not have diagnosis in axis II ; Lack of drug dependence and lack of major neurological complications in terms of history; Written consent to participate in the study ; Right-handed ; Unchanged drug in the last month and the lack of psychotherapy in 8 weeks Exclusion criteria:Other disorders in axis I and II ; Having implant or prosthesis or metal in skull ; Patient satisfaction or waiver of him; Pregnancy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intensity of Obsession Compulsion Symptoms. Timepoint: Before intervention- after last intervention and 1 month after last intervention. Method of measurement: YALE-BROWN (Y-BOCS) Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Mehdi Rezaei

Mazandaran University of Medical Sciences

drrezaei@hotmail.com+98 11 3328 3886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026