The Comparison of two combination of dexamethasone and ondansetron with dexamethasone and plasil on Nausea, vomiting and chills

The Comparison of two combination of dexamethasone and ondansetron with dexamethasone and plasil on Nausea, vomiting and chills in patients undergoing laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017010923559N7

Enrollment

100

Registered

2017-03-20

Start date

2017-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystectomy. Calculus of gallbladder with acute cholecystitis

Interventions

Intervention 1: The first group received Intravenous dexamethasone (8 mg) and Intravenous ondansetron during surgery. Intervention 2: The second group received Intravenous dexamethasone (8 mg) and Int

Prevention

Diagnosis

The first group received Intravenous dexamethasone (8 mg) and Intravenous ondansetron during surgery.

The second group received Intravenous dexamethasone (8 mg) and Intravenous Plasil (10 mg) during surgery.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Biliary colic pain, Uncomplicated gallstone, Consent to participate in the study. Exclusion criteria: Medical complications, sensitivity to dexamethasone, ondansetron and Plazil, complicated cholecystectomy, Open surgery is indicated for gallstones, lack of consent to participate in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausea. Timepoint: Within 24 hours of operation. Method of measurement: Through a score of N & V.;Vomit. Timepoint: Within 24 hours of operation. Method of measurement: Through a score of N & V.;Shivering. Timepoint: Within 24 hours of operation. Method of measurement: shivering visual scale.	—

Secondary

Measure	Time frame
Dizziness. Timepoint: Within 24 hours of operation. Method of measurement: question of patient.;Headache. Timepoint: Within 24 hours of operation. Method of measurement: MDAS questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoud Entezari Aal

Ardabil University of Medical Sciences

m.entezari@arums.ac.ir+98 45 3225 1688

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026