Effect of vitamin C on pain after surgery for forearm fracture

The effect of Adding Vitamin C to Bier Block on the Occurrence of Complex Regional Pain Syndrome (CRPS) Following Distal Radius Fracture Surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170109031852N4

Enrollment

Registered

2020-03-22

Start date

2017-11-22

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Isolated and extra-articular fracture of distal radius. Fracture of lower end of radius

Interventions

Intervention 1: Vitamin C 500 mg will be added to local anesthetic in Bier block. All patients in both groups will receive daily oral vitamin C 500 mg for 6 weeks postoperatively. Intervention 2: St

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with isolated and extra-articular distal radius fractures

Exclusion criteria

Exclusion criteria: Chronic use of analgesics

Design outcomes

Primary

Measure	Time frame
Incidence of Complex Regional Pain Syndrome (CRPS). Timepoint: 2, 4, 6 and 12 weeks after treatment. Method of measurement: Based on CRPS diagnostic criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahzad Alimian

Iran University of Medical Science

alimian.m@iums.ac.ir+98 21 6435 2326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026