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A Comparative evaluation of the effect of Estradiol jell and Valerate Estradiol tablet in preparing endometrium .

A Comparative evaluation of the effect of Estradiol jell and Valerate Estradiol tablet in preparing endometrium for frozen embryo transfer cycle without agonist suppression.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201701083950N5
Enrollment
100
Registered
2017-03-13
Start date
2016-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility associated with anovulation. Female infertility, unspecified

Interventions

Intervention 1: Intervention group 1: the first day of menstrual cycle the amount of estradiol was checked. From the first day of menstrual cycle 6 mg of estradiol was daily given. After one week, ult
Treatment - Drugs
Intervention group 1: the first day of menstrual cycle the amount of estradiol was checked. From the first day of menstrual cycle 6 mg of estradiol was daily given. After one week, ultra-sound was don
Intervention group 2: from the first day of menstrual cycle 4.5 mg of estradiol jell equaling three line of the ruler and 4 mg of oral estradiol in the upper arm or thigh area was used. After one week

Sponsors

Vice Chancellor for Research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients candidate for freeze embryo transfer; age 20-45 years old. Exclusion criteria: patients candidate for fresh embryo transfer; ovarian failure; reduced response to ovarian stimulation and oocyte recipient candidates; patients with hyperstimulation ( ovaries hyperrstimulation ) that have not done embryo transfer in fresh cycles; fetus with bad quality.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Endometrial thickness. Timepoint: One week after treatment. Method of measurement: Vaginal sonography.;Estradiol quantity. Timepoint: One week after treatment. Method of measurement: Lab Test.

Secondary

MeasureTime frame
Clinical Pregnancy. Timepoint: Three weeks after do positive of pregnancy teset. Method of measurement: Transvaginal sonography.;Chemical pregnancy. Timepoint: 14 days after embryo transfer. Method of measurement: B-HCG Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmal Shoman

Reproductive Health Research Center

amani162@yahoo.com+98 21 6658 1616

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026