The effect of albuterol spray on hypoxia and bronchospasm in patients with chronic obstructive pulmonary disease (COPD)

The effect of albuterol spray-on hypoxia and bronchospasm in patients with chronic obstructive pulmonary disease (COPD) under general anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170108031818N1

Enrollment

120

Registered

2021-11-29

Start date

2021-11-06

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pulmonary obstruction(COPD). J44. 9

Interventions

Intervention group: The patient receives 2 puffs of albuterol spray (2.5 micrograms per puff) 20 minutes before anesthesia.

Eligibility

Sex/Gender

All

Age

35 Years to No maximum

Inclusion criteria

Inclusion criteria: The patient is a smoker ASA is class 1 and 2 The patient has a history of COPD

Exclusion criteria

Exclusion criteria: The patient develops bronchospasm during the operation The surgery lasted more than 3 hours Pulmonary artery pressure is greater than 25 mm Hg Changes in blood pressure, heart rate and drop in severity by 20% of baseline

Design outcomes

Primary

Measure	Time frame
Wheezing. Timepoint: once. After intubation of the endotracheal tube. Method of measurement: Using a medical earphone, the patient's lungs can be heard.;Frequent coughing. Timepoint: 2 times - before anesthesia and after ecstasy. Method of measurement: By observing the appearance of the patient.;Bronchospasm. Timepoint: 1 time. After anesthesia. Method of measurement: If the patient is intubated, bronchospasm is suspected by the anesthesia ventilator storage bag if the storage bag tightens and is considered positive and recorded.	—

Measure

Time frame

Wheezing. Timepoint: once. After intubation of the endotracheal tube. Method of measurement: Using a medical earphone, the patient's lungs can be heard.;Frequent coughing. Timepoint: 2 times - before anesthesia and after ecstasy. Method of measurement: By observing the appearance of the patient.;Bronchospasm. Timepoint: 1 time. After anesthesia. Method of measurement: If the patient is intubated, bronchospasm is suspected by the anesthesia ventilator storage bag if the storage bag tightens and is considered positive and recorded.

—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmahrokh maddah

Gorgan University of Medical Sciences

mehravar10261@goums.ac.ir+98 17 3217 7419

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026