Anal fissure. Chronic anal fissure
Conditions
Interventions
Intervention 1: Intervention group: ITM based protocol local herbal gel from extract of Astragalus fasciculifolius, Comiphora mukul, Syzygium aromaticum:clove, Aloe vera and Allium ampeloprasum, 1
Treatment - Drugs
Intervention group: ITM based protocol local herbal gel from extract of Astragalus fasciculifolius, Comiphora mukul, Syzygium aromaticum:clove, Aloe vera and Allium ampeloprasum, 1 gram BID, and di
Control group: diltigel, 1 gram BID and high fiber diet is recommended for 4 weeks .
Sponsors
Vice Chancellor for Research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: female with chronic anal fissure between 20 and 60 years old with pain and irritation; no fistula or abscess in the anal area; no history of anal cancer. Exclusion criterion: patients with underlying diseases (crohn disease, ulcerative colitis ); sensitivity to drug ingredients; pregnancy or lactation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before the start of intervention, 1, 2, 4 weeks after intervention and 4 weeks after the end of intervention. Method of measurement: VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Irritation. Timepoint: Before the start of intervention, 1, 2, 4 weeks after intervention and 4 weeks after the end of intervention. Method of measurement: VAS.;Bleeding. Timepoint: Before the start of intervention, 1, 2, 4 weeks after intervention and 4 weeks after the end of intervention. Method of measurement: VAS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSedigheh Taavakoli Dastjerdi
Mashhad University of Medical Sciences
Outcome results
None listed