Condition 1: preeclampsia. Condition 2: gestational hypertention. Pre-eclampsia, unspecified Gestational [pregnancy-induced] hypertension without significant proteinuria
Conditions
Interventions
Intervention 1: In misoprostol group: 25 micro grams of misoprostol tablet was administered sublingually every 4 hours up to maximum dose of 6 during cervical ripening. Intervention 2: In foley cathet
Treatment - Drugs
Treatment - Devices
In misoprostol group: 25 micro grams of misoprostol tablet was administered sublingually every 4 hours up to maximum dose of 6 during cervical ripening.
In foley catheter group: A 16 F foley catheter was inserted through internal os of cervix under aseptic condition and it was inflated with 60 cc of sterile salin. This intervention was performed durin
Sponsors
Research assistance of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1- pregnant women with preeclampsia or gestational hypertension 2- Singleton pregnancy 3- Gestational age of 26 weeks or more 4- Absence of active labour 5- Cephalic presentation 6- Unfavorable cervix ( bishop score of 6 or less) 7- Normal FHR 8- Intact membrane. Exclusion Criteria: 1- Hypersensitivity to Prostaglandins 2- Previous Cesarean section 3- Previous uterine scar 4- Macrosomia 6- lethal congenital anomalies 7- Placenta previa.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interval between induction commencement and obtaining bishop score of 6. Timepoint: During intervention. Method of measurement: In hour unit obtained by manual vaginal exam. | — |
Secondary
| Measure | Time frame |
|---|---|
| Delivery before 24 hours. Timepoint: up to 24 hours after intervention. Method of measurement: in hour unit obtained by questionnaire.;Neonatal complications. Timepoint: up to 24 hours after birth. Method of measurement: questionnaire and apgar score.;Oxytocin requirement. Timepoint: during intervention. Method of measurement: questionnaire.;Maternal complications. Timepoint: 24 hours after delivery. Method of measurement: questionnaire.;Duration of the second stage of delivery. Timepoint: maximum 3 hours after complete dilatation and effacement. Method of measurement: in minute unit obtained by questionnaire.;Cesarean delivery incidence. Timepoint: up to 48 hours after intervention. Method of measurement: percentage unit obtained by questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElahe Hassanzadeh
Mashhad University of Medical Sciences
Outcome results
None listed